唾液,脑脊液,眼泪,幽默和羊水等生物液都含有脂质,这些脂质都可以提供有关与疾病有关的脂质变化的信息。
Saliva | 在追求口腔癌,糖尿病和慢性口腔炎性疾病(例如牙周炎)的生物标志物来源的可用性,采样,尤其是相关性,这使唾液成为研究脂质概况相关的疾病变化的重要生物基础。 |
脑脊髓液 | Cerebrospinal fluid (CSF) is considered a promising source of biomarkers for neurodegenerative diseases such as Alzheimer's, dementia, and chronic neurological diseases. It is anatomically close to the brain. CSF lipidomics analysis is suitable for exploring lipid homeostasis in brain diseases, thereby reflecting disease-related changes. |
眼泪 | 泪液充当招牌,可以理解眼部疾病的病因和/或跟踪预后/对治疗的反应。脂质除了蛋白质外,是催泪膜的主要成分之一,具有内部粘蛋白层,中间水层和外脂质层。我们对眼泪的综合脂质分析涵盖了17个主要脂质类别,其中包括600多种脂质类型。 |
水性幽默 | While tears immediately reflect the changes occurring at the cornea eyelids, aqueous humor alterations in tear constituents also reflects the disease mediated changes happening in the posterior portion of the eye. |
羊水 | 羊水脂质组可以帮助了解疾病的脂质变化,例如自发性早产和期限分娩,术语临床绒毛膜炎,胎儿高脂血症和呼吸窘迫综合征,并加速相关疾病机制的研究。 |
Therefore, comprehensive lipidomic data from biofluids is likely to be point-of-care diagnostics for certain targets validated to be useful biomarkers in disease. Creative Proteomics provides comprehensive biofuild lipidomics services from lipid extraction, lipid detection and data analysis for biomedical research institutions, biotechnology and pharmaceutical companies.
基于液相色谱 - 质谱法(LC-MS)技术,创造性蛋白质组学对生物流体样品中脂质分子的无偏检测。
图。1。生物培养的无靶向脂肪组学分析服务的工作流程。
According to different experimental schemes, we usually need 1-200 ul biological samples for our untargeted lipidomics services.
Avoid repetitive freeze-thaw cycles, store at -80°C.
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