Dihexosylceramides分析服务- Lipidomics|Creative Proteomics

Dihexosylceramides分析服务

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With integrated set of separation, characterization, identification and quantification systems featured with excellent robustness & reproducibility, high and ultra-sensitivity, Creative Proteomics has developed a reliable and reproducible method using highly sensitive LC-MS/MS method for the rapid identification and quantification of dihexosylceramide in different sample types, which can satisfy the needs of academic and industrial study in your lab.

Overview

Dihexosylceramides靶向脂质组学

Dihexosylceramide（Cerg2或Dihexcer）是糖磷脂脂。它们的结构由连接到中性二糖分子的神经酰胺主链组成。神经酰胺骨架包含两个烃链：通过酰胺键连接到脂肪酸的长链底部。脂肪酸和长链碱的长度变化，羟基化并包含双键。

Many dihexosylceramides are key intermediates in the biosynthesis of glycosphingolipids, which contain three or more sugar molecules, such as globulins and gangliosides. However, they are essential for cell function and are particularly important for the formation of lipid rafts in the cells of the innate immune system. They bind to pathogens and mediate immune and inflammatory responses. In addition, abnormal metabolism of dihexylceramide is associated with cancer, cardiovascular disease, inflammation and multiple sclerosis.

当前，一种使用高度敏感的LC-MS/MS平台来识别和量化不同样本类型中CERG2的一种可靠且可重复的方法，已经建立了Creative Proteomics的科学家，可以满足您实验室中的学术和工业研究的需求。

Advantages of Our Dihexosylceramide Analysis Service

We routinely cover a rich variety of sample types, including cells, conditioned medium, subcellular compartments, exsome, tissue, blood, plasma, urine for our customer. Still, our services require only minimal sample amounts per analysis.
With integrated set of separation, characterization, identification and quantification systems featured with excellent robustness & reproducibility, high and ultra-sensitivity, Creative Proteomics provides reliable, rapid and cost-effective CerG2 targeted lipidomics services.
向我们发送样本，并在2-4周内接收数据。

List of Detectable Dihexosylceramide at Creative Proteomics

DiHexCer 30:1;2

DiHexCer

Dihexcer 34：1; 2

我们的二己糖基酰胺分析服务的技术过程

Dihexosylceramide分析服务的工作流程

Structural details:species level
精确: pmol & mol%
确定的变体:> 50
Delivery time:2-4周
样本要求
Blood/plasma: 500 ul/sample
组织：200 mg/样品
细胞：1x10⁷/sample

A minimum of 6 replicate plates or wells per condition are required.
After the sample is collected, it will be stored at -80°C immediately and transported by dry ice.
试管应清楚用样品标识符标记，并包括伴随货物的样品列表的纸质副本。运送样品时，请包括所有可用的示例信息。

可交付成果

Experimental procedure
液相色谱和MS的参数
Purity analysis report
MS原始数据文件和MS数据质量检查
Hexylceramide quantitative result data
Custom analysis report

基于高度稳定，可重现和高度敏感的分离，表征，识别和定量分析系统，结合LC-MS/MS，我们提供可靠，快速和成本效益的CERG2分析服务。如果您对我们的CERG2有针对性的脂肪委员会服务有任何疑问，请contact us。

Dihexosylceramides分析服务