Human Phospho ErbB/Her Signaling Protein Array, 122 Target proteins (HA-PER-PA)

目标物种

Human

Target Names

Abl1 (Thr754/735), Abl1 (Tyr204), AKT (Ser473), AKT (Thr308), AKT (Tyr326), AKT1 (Ser124), AKT1 (Ser246), AKT1 (Thr450), AKT1 (Thr72), AKT1 (Tyr474), AKT2 (Ser474), BAD (Ser112), BAD (Ser134), BAD (Ser136), BAD (Ser155), BAD (Ser91/128), c-Abl (Tyr412), Calmodulin (Thr79/Ser81), CaMK1-a (Thr177), CaMK1-b, CaMK2 (Thr305), CaMK2 (Thr286), CaMK2-b/g/d (Thr287), CaMK4 (Thr196/200), Catenin beta (Ser33), Catenin beta (Ser37), Catenin beta (Thr41/Ser45), Catenin beta (Tyr489), Catenin beta (Tyr654), Caveolin-1 (Tyr14), CBL (Tyr700), CBL (Tyr774), CrkII (Tyr221), CrkL (Tyr207), Dok-1 (Tyr362), Dok-1 (Tyr398), Dok-2 (Tyr299), E-Cadherin, EGFR (Ser1070), EGFR (Thr678), EGFR (Thr693), EGFR (Tyr1016), EGFR (Tyr1069), EGFR (Tyr1092), EGFR (Tyr1110), EGFR (Tyr1172), EGFR (Tyr1197), EGFR (Tyr869), FAK (Ser910), FAK (Tyr397), FAK (Tyr407), FAK (Tyr576), FAK (Tyr861), FAK (Tyr925), FKHR (Ser256), FKHR (Ser319), FOXO1/3/4-PAN (Thr24/32), FOXO1A (Ser329), Gab1 (Tyr627), Gab1 (Tyr659), Gab2 (Tyr643), GSK3a (Ser21), GSK3a/b (Tyr216/279), GSK3b (Ser9), HER2 (Tyr1221/Tyr1222), HER2 (Tyr1248), HER2 (Tyr877), HER3/ErbB3 (Tyr1222), HER3/ErbB3 (Tyr1289), HER4/ErbB4 (Tyr1284), JAK1 (Tyr1022), JAK2 (Tyr1007), JAK2 (Tyr221), JNK1/2/3 (Thr183/Tyr185), MAP3K1/MEKK1 (Thr1381), MDM2 (Ser166), MEF2A (Ser408), MEF2A (Thr312), MEF2A (Thr319), mTOR (Ser2448), mTOR (Ser2481), mTOR (Thr2446), NMDAR1 (Ser897), NMDAR2B (Tyr1472), p130Cas (Tyr165), p130Cas (Tyr410), p44/42 MAPK (Thr202), p44/42 MAPK (Tyr204), p53 (Ser15), p53 (Ser392), P70S6K (Ser371), P70S6K (Ser424), P70S6K (Thr229), P70S6K-beta (Ser423), PAK1 (Ser204), PAK1 (Thr212), PAK1/2 (Ser199), Paxillin (Tyr118), Paxillin (Tyr31), PI3K-p85-a (Tyr607), PI3K-p85-a/g (Tyr467/Tyr199), PKC pan activation site, PLC-gamma 1 (Tyr771), PLC-gamma 1 (Tyr783), PLC-gamma 2 (Tyr1217), PLC-gamma 2 (Tyr753), Rac1/cdc42 (Ser71), Raf1 (Phospho-Ser621), Raf1 (Ser259), Raf1 (Ser338), Raf1 (Tyr341), Shc (Tyr349), Shc (Tyr427), SHP-2 (Tyr542), SHP-2 (Tyr580), Src (Ser75), Src (Tyr418), Src (Tyr529), SYK (Tyr348), SYK (Tyr525), VAV1 (Tyr174), XIAP (Ser87)

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Storage

Store at 4°C for at least 6 months. For extended storage, store Biotin Reagent and Coupling Reagent at -20°C and all other reagents including array sildes undiluted at 4°C for no more than 6 months.

Solid Support

Glass

OUTPUT

Semi-Quantitative

Principle of The Assay

Elisa Based Antibody Array

Suitable Samples

Suitable for all liquid sample types, such as Cell Culture Supernatants, Cell Lysates, Tissue Lysates, Plasma, and Serum. Some of the products may suitable for frozen or FFPE tissue lysates. Contact for detailed informations.

Suggested Application

Qualitative protein profiling
Identify candidate biomarkers
Key Factors Screening
Biological Process Confirming
Biomarker Validation
Validation of Antibody Array Results
Phosphorylation changes at specific sites
Normal Range Establishing
Compare profiles of normal diseased or treated samples

Number of Targets

122