超过200 nt且没有编码势或缺乏编码> 100个氨基酸的RNA转录本被归类为LNCRNA。在包括植物在内的各种真核生物中都发现了许多LNCRNA。LNCRNA是各种生物过程的重要调节剂,并通过多种机制起作用。
代谢组是生物体表型的基础和直接实施例。代谢物是内部和外部调节下生物体基因转录的最终结果,并且是生物体表型的物质基础。在系统生物学研究的时代,生物发育过程是复杂且可变的,并且基因调节网络很复杂。仅通过一种类型的组织学对系统生物学的研究可能是单方面的。
Creative Proteomics provides services combining LncRNA and metabolomic analysis. A large number of differential LncRNAs are obtained by LncRNA sequencing, and these differential LncRNAs can be correlated with differential metabolites obtained from metabolomic analysis to further delve into regulatory and expressed genes and analyze intrinsic changes in the organism. The key pathways of metabolite change can be targeted to construct core regulatory networks to comprehensively explore the growth and development of organisms and stress mechanisms, so as to explain biological issues as a whole.
样本类型 | LncRNA sample size | Metabolomics sample size |
植物组织样品 | ≥1.5g(增加糖含量较高样品的样本量) | ≥3G,最小1G |
动物组织样品 | ≥1g(脂肪和其他RNA产量低的脂肪和其他组织) | ≥200 mg |
动植物样品 | ≥1×107 | 1×107 |
RNA |
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植物生长和发育,农艺形状
植物颜色,营养品质
Plant abiotic stresses, biotic stress mechanisms
植物功能活性成分途径研究
动物的成长与发展
Animal Nutrition
动物疾病
环境适应
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