神经疾病代谢组学服务
Neurological disorders, a small group of medical conditions that affect the nervous system, are more than 600 different diseases, including genetic disorders, infections, cancers, seizures (e.g., epilepsy), cardiovascular diseases (e.g., stroke), congenital and developmental disorders (e.g., spina bifida), and degenerative diseases (e.g., multiple sclerosis, Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis).
Metabolomics is the qualitative and quantitative analysis of all small molecule metabolites in an organism or cell, and the search for relative relationships between metabolites and physiopathological changes.
Creative Proteomics is based on a variety of highly sensitive analytical techniques to identify metabolites involved in disease development by comparative assays analyzing metabolomic features in different samples from experimental and control groups. These differentially expressed substances can provide new insights into individual metabolic profiles to identify diagnostic or prognostic biomarkers, identify drug target candidates, or reveal potential new hypothesis-generating pathways. Studying the characteristic metabolic alterations in neurological diseases can help to understand the endogenous metabolic pathogenesis of the disease. Metabolomic markers also have the potential to improve diagnosis, patient follow-up, and clinical trial outcomes.
神经疾病代谢组学解决方案
01
Metabolomic analysis of central nervous system tumors
Analysis of metabolite differences between healthy individuals and glioma models. CNS tumor biomarker detection. Analysis of drug metabolism in drug development.
02
Metabolomic analysis of central nervous system trauma
Metabolic profiling to explore the mechanisms of CNS trauma.
03
Metabolomic analysis of Alzheimer's disease and related dementias
代谢分析研究阿尔茨海默氏病的发病机理。对照组和实验组的代谢物含量变化的比较分析。生物标志物检测。
04
Metabolomic analysis of amyotrophic lateral sclerosis/motor neuron disease
Metabolic profiling. Analysis of changes in metabolite levels in control and experimental groups. Biomarker detection.
05
Metabolomic analysis of Parkinson's disease and movement disorders
Metabolic profiling to investigate the pathogenesis of Parkinson's disease. Comparative analysis of metabolite content changes in control and experimental groups. Biomarker assay.
神经疾病的代谢组学分析过程

代谢组学分析的技术平台
Multiple analytical platforms, including GC-MS, LC-MS, UPLC-MS. Thousands of metabolites can be screened from a single biological sample, providing a comprehensive approach for probing disease mechanisms.
Chromatography |
Mass Spectrometry |
GC (Q Exactive) (- mode MS) HPLC: HILIC (+/- mode MS) HPLC: RP C18 (+/-mode MS) IC (- mode MS) |
q精确的MS Orbitrap Tribrid MS |
Creative Proteomics是生物制药研究的良好合作伙伴,在代谢组学分析方面拥有丰富的经验。我们为代谢组学分析方向提供神经疾病的解决方案,从而加快了科学新视野的探索。如果您想了解更多,请联系我们。期待与您合作。
仅用于研究。不用于诊断过程。