肿瘤研究代谢组学服务

代谢组学将高通量，高分辨率的分析技术与生物信息学相结合，以研究新陈代谢，并为生物提供独特的观点。

Genomics, transcriptomics, proteomics, and metabolomics detect and identify various molecules and study their functions at the DNA, mRNA, protein, and metabolite levels, respectively. Transcriptomics and proteomics are not yet able to fully express the full range of functions of an organism. Metabolomics quantifies the time-dependent multiplicity of metabolites produced by an organism's genetic modifications and by pathophysiological stimuli. The aim is to systematically elucidate the function of an organism by analyzing compounds at different developmental stages or in different growth environments and following their metabolic pathways with the aim of being able to map the full range of complex interactions between genes, proteins and metabolites.

肿瘤和癌症是一种复杂的疾病,multiple factors are involved causing disturbance of the functional balance of all systems of the body. Their metabolic effects are significantly different from those of normal tissues. The quantitative analysis of all small molecule metabolites in a given biological system by metabolomics at a given time and condition allows to quantify the overall situation of biological endogenous metabolites or to analyze the patterns that cause their endogenous and exogenous changes.

不同的体液具有不同的起源，分布和功能，因此包含差异很大的代谢物成分。创意蛋白质组学为肿瘤学研究提供了代谢组学解决方案，以加快相关科学研究项目的进展。可以研究许多生物组织和液体的代谢组学，包括唾液，血液，尿液，胆汁，乳液，脑脊液和组织提取物。

Oncology Research Metabolomics Solutions

• Identification of tumor-specific metabolites

代谢组学寻找来自人体动态代谢途径的肿瘤特异性代谢产物，并且在所有阶段都有良好的应用。特别是，它在疾病模式分类和病理分期中具有显着优势。

• 蛋白质代谢物（氨基酸）：肿瘤蛋白质合成和分解代谢的特异性可用于标记检测。
• Nucleic acid metabolites (nucleotides): tumor cells are metabolically vigorous, with accelerated DNA and RNA synthesis and increased nucleotides, which can provide many indicators of nucleotide metabolism.
• Lipid metabolites: Analysis of lipid concentration and localization changes during various types of malignancies and inflammation.
• Glucose metabolites: Analysis of changes in sugar metabolism, such as purine and pyrimidine metabolism, glycolipid metabolism, and energy metabolism.

• 分析肿瘤的分子机制与系统生物学结合

Monitoring changes in the transcriptional up- or down-regulation effects of oncogenes reveals the relationship between genes and phenotypes and provides new ideas for the study of tumor mechanisms.

Metabolomics Analysis Process for Oncology Research

代谢组学分析的技术平台

Multiple analytical platforms, including GC-MS, LC-MS, UPLC-MS. Thousands of metabolites can be screened from a single biological sample, providing a comprehensive approach for probing disease mechanisms.

Creative Proteomics is a well-established partner in biopharmaceutical research and has extensive experience in metabolomics analysis. We provide solutions for oncology research in the direction of metabolomics analysis, accelerating the exploration of new horizons in science. If you want to know more, please联系我们。期待与您合作。